Publications
Peer reviewed papers (15 papers)
15. Y. Ochi, A. Kon, T. Sakata, M. M. Nakagawa, N. Nakazawa, M. Kakuta, K. Kataoka, H. Koseki, M. Nakayama, D. Morishita, T. Tsuruyama, R. Saiki, A. Yoda, R. Okuda, T. Yoshizato, Y. Shiozawa, Y. Nannya, S. Kotani, Y. Kogure, N. Kakiuchi, T. Nishimura, H. Makishima, L. Malcovati, A. Yokoyama, K. Takeuchi, E. Sugihara, T. A. Sato, M. Sanada, A. Takaori-Kondo, M. Cazzola, M. Kengaku, S. Miyano, K. Shirahige, H. I. Suzuki, S. Ogawa
“Combined Cohesin-Runx1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes.”
Cancer Discovery, in press (2020)
14. Bo Yang, H. Wolfenson, V. Y. Chung, N. Nakazawa, S. Liu, J. Hu, R. YJ. Huang, M. P. Sheetz
“Stopping transformed cancer cell growth by rigidity sensing”
Nature Materials, Vol. 19, 239-250 (2020)
13. M. Inaki, R. Hatori, N. Nakazawa, T. Okumura, T. Ishibashi, J. Kikuta, M. Ishii, K. Matsuno, H. Honda
“Chiral cell sliding drives left-right asymmetric organ twisting”
eLIFE, Jun. 12;7 (2018)
12. S. Le, X. Hu, M. Yao, H. Chen, M. Yu, X. Xu, N. Nakazawa, F. M. Margadant, M.P. Sheetz, J. Yan
“Mechanotransmission and Mechanosensing of Human alpha-Actinin 1”
Cell Reports, Vol. 21, No.10, 2714-2723 (2017)
11. N. Nakazawa, A.R. Sathe, G.V. Shivashankar, and M.P. Sheetz,
“Matrix mechanics controls FHL2 movement to the nucleus to activate p21 expression”
Proc. Natl. Acad. Sci. USA, Vol.113, No.44, E6813-E6822 (2016)
10. X. Hu, C. Jing, X. Xu, N. Nakazawa, V. W. Cornish, F. Margadant, M. P. Sheetz,
“Cooperative Vinculin binding to Talin mapped by time resolved super resolution microscopy”
Nano letters, Vol.16, No.7, 4062-4068 (2016)
9. T. Okumura, T. Sasamura, M. Inatomi, S. Hozumi, M. Nakamura, R. Hatori, K. Taniguchi,
N. Nakazawa, E. Suzuki, R. Maeda, T. Yamakawa, and K. Matsuno
“Genetic analysis of Drosophila Class I Myosin genes in Left-Right asymmetric development.”
Genetics, Vol.199, 1183-1199 (2015)
8. R. Hatori, T. Ando, T. Sasamura, N. Nakazawa, M. Nakamura, K. Taniguchi, S. Hozumi, J. Kikuta, M. Ishii, K. Matsuno
“Left-right asymmetry is formed in individual cells by intrinsic cell chirality.”
Mechanisms of Development, Vol.133, 146-162 (2014)
7. M. Nakamura, K. Matsumoto, Y. Iwamoto, T. Muguruma, N. Nakazawa, R. Hatori, K. Taniguchi, R. Maeda, K. Matsuno
“Reduced cell number in the hindgut epithelium disrupts hindgut left–right asymmetry in a mutant of , encoding a RhoGEF, in embryos.”
Mechanisms of Development, Vol.130, 169-180 (2013)
6. N. Nakazawa, K. Taniguchi, T. Okumura, R. Maeda, and K. Matsuno
“A novel Cre/loxP system for mosaic gene expression in the Drosophila embryo.”
Developmental Dynamics, Vol.241, 965-974 (2012)
5. J. Kuroda, M. Nakamura, M. Yoshida, H. Yamamoto, T. Maeda, K. Taniguchi, N. Nakazawa, R. Hatori, A. Ishio, A. Ozaki, S. Shimaoka, T. Ito, H. Iida, T. Okumura, R. Maeda, K. Matsuno
“Canonical Wnt signaling in the visceral muscle is required for left-right asymmetric development of the midgut.”
Mechanisms of Development, Vol.128, 625-639 (2012)
4. T. Yamakawa, K. Yamada, T. Sasamura, N. Nakazawa, M. Kanai, E. Suzuki, M. E. Fortini, and K. Matsuno
“Deficient Notch signaling associated with neurogenic is compensated for by the unfolded protein response in Drosophila.”
Development, Vol.139, 558-67 (2012)
3. K. Taniguchi, R. Maeda, T. Ando, T. Okumura, N. Nakazawa, R. Hatori, M. Nakamura, S. Hozumi, H. Fujiwara, K. Matsuno
“Chirality in Planar cell shape contributes to left-right asymmetric epithelial morphogenesis.”
Science, Vol.333, 339-341 (2011)
2. T. Okumura, H. Fujiwara, K. Taniguchi, J. Kuroda, N. Nakazawa, M. Nakamura, R. Hatori, A. Ishio, R. Maeda, K. Matsuno
“Left-right asymmetric morphogenesis of the anterior midgut depends on the activation of a non-muscle myosin II in Drosophila.”
Developmental Biology, Vol.344, 693-706 (2010)
1. S. Hozumi, R. Maeda, M. T. Kanai, T. Okumura, K. Taniguchi, Y. Kawakatsu, N. Nakazawa, R. Hatori, and K. Matsuno
“Head region of unconventional Myosin I family members is responsible for the organ-specificity of their roles in left-right polarity in Drosophila.”
Developmental Dynamics, Vol.237, 3528-3537 (2008)
Review article (1 article)
1. N. Nakazawa* and M. Kengaku (*Corresponding author)
“Mechanical regulation of nuclear translocation in migratory neurons”
Frontiers in Cell and Developmental Biology, 8:150 (2020)
Preprint (1 paper)
1. Bo Yang, H. Wolfenson, N. Nakazawa, S. Liu, J. Hu, M. P. Sheetz,
“Stopping transformed cell growth with cytoskeletal proteins: Turning a Devil into an Angel”
Invited reviews (3 reviews)
3. N. Nakazawa, M. Kengaku
“Mechanobiology of neuronal migration in the developing brain” (Japanese)
Seitai no kagaku, Vol.70, No.4 (2019)
2. N. Nakazawa
“My experience in overseas research -Focusing on relationship-” (Japanese)
Experimental Medicine, Vol.33, No.18 (2015)
1. N. Nakazawa, K. Taniguchi, R. Maeda, T. Ando, K. Matsuno
“A novel mechanism for the left-right asymmetric morphogenesis.” (Japanese)
Experimental Medicine, Vol.30, No.1, 75-78 (2012)
Talks
Invited talks (13 talks)
13. N. Nakazawa, G. Grenci, M. Kengaku
“Mechanical stress by extracellular confinement trigger a mode transition of neuronal migration”
Fukuoka international congress center, Fukuoka, Dec. 3-6, 2020
“Novel functions of cytoskeletal molecules as mediators of signal transduction"
in the 42nd annual meeting of the molecular biology society of Japan”
12. N. Nakazawa
“Mechano-responses to the extracellular environment in migratory neurons”
Benesse art site Naoshima, Kagawa, Sep. 3-4, 2019
“1st Mechanobiology workshop in Japan”
11. N. Nakazawa
“Mechano-responses to the extracellular environment in migratory neurons”
National Institute for Materials Sciences (NIMS), Mar. 3-8, 2019
“3rd International Symposium on Nanoarchitectonics for Mechanobiology”
10. N. Nakazawa, W. Theoputra, J. Zixian, M. Utsunomiya, G. Grenci, S. H. Yoshimura, M. Kengaku
“Nuclear mechanics in migratory cerebellar granule cells ”
Osaka University, Nambu Yoichiro Hall, Japan, Aug. 25-26, 2018
“Looking to the future of Developmental Cell Biology Symposium”
9. N. Nakazawa, H. Umeshima, Y. K. Wu, M. Kengaku
“Cellular responses to mechanical influences of the extracellular environment ”
Hikone view hotel, Shiga, Japan, June 25-26, 2018
“iCeMS retreat 2018, Young researcher talk ”
8. N. Nakazawa
“Cellular responses to mechanical influences of the extracellular environment ”
Hokkaido University, Sapporo, Japan, May 25, 2018
“The Japan Society of Mechanical Engineers Hokkaido Branch “Biomechanics Research Meeting”
33rd Seminar ”
7. N. Nakazawa, H. Umeshima, Y. K. Wu, M. Kengaku,
“Nuclear mechanics in migratory neuron in Cerebellum” (Japanese)
Hitotubashi hall, Tokyo, Japan, Dec. 19-21, 2017
“Jisedai-nou project-Symposium 2017-”
6. N. Nakazawa, Aneesh Sathe, G. V. Shivashankar, Michael Sheetz
“A molecular mechanism of gene regulation by matrix mechanics -A moving story of FHL2 and Force-”
Kumamoto university, Kumamoto, Japan, Sep. 19, 2017
“International symposium on mechanobiology with its cutting edge and diversity
in the 55th annual meeting of the biophysical society of Japan”
5. N. Nakazawa
“Matrix mechanics controls FHL2 movement to the nucleus to activate p21 expression” (Japanese)
Konan University, Kobe, Japan, Jan. 18, 2017
“Lecture at the Science Live Ticket part 26”
4. N. Nakazawa
“My research experience in Singapore” (Japanese)
Pacific Yokohama, Yokohama, Japan, Dec. 1, 2016
“Forum organized by UJA in The 39th Annual Meeting of the Molecular biological society of Japan”
3. N. Nakazawa
“A mechano-response mediated by LIM-domain protein” (Japanese)
RIKEN Singapore, Helios, Nov. 21, 2014
“Seminar in Japanese Association of Scientists in Singapore”
2. N. Nakazawa
“Quantification of mechanical force driving the left-handed twisting of the gut epithelial tube in Drosophila”
Mechanobiology Institute, National University of Singapore, Singapore, Oct. 1, 2012
“Seminar in Mechanobiology institute”
1. N. Nakazawa, K. Matsuno
“Quantification of mechanical force driving the left-handed twisting of the gut epithelial tube in Drosophila”
RIKEN CDB, Kobe, Japan, June 26, 2012
“RIKEN CDB Brainstorming workshop”
Oral presentations selected by session organizers (2 talks)
2. N. Nakazawa, R. Maeda, S. Sugita, T. Matsumoto and K. Matsuno
“Quantification of mechanical force driving the left-handed twisting of the gut epithelial tube in Drosophila”
The Jikei University School of Medicine, Tokyo, Oct. 2012.
The 10th Japanese Drosophila Research Conference (JDRC10)
1. N. Nakazawa, M. Nakamura, K. Taniguchi, T. Okumura, H. Yamamoto, R. Hatori, A. Ishio, A. Ozaki, R. Maeda and K. Matsuno
“A genetic screen of the Drosophila second chromosome to identify genes involved in the left-right asymmetric development of the embryonic gut”
Marriott Wardman Park, Washington DC, Apr. 2010
51th Drosophila Research Conference